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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11e19487792defaa286399cac00d2cad5f242a98f7cdf0d8ee4d7f886929f01d' 
  AND token = 'hzh6fcs7jn80rDhd3n/10VLuOU2kkcCgPNVE1RER1PE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}