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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4998d6d7d6d54b4176e9304ebab7360997a827e11d3c0e4bd6ada4331b5c042' 
  AND token = 'ZtHh4Xol7jMGq4fbw4DgyQWaaeyxauvyyqZG9NQjyQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}