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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d179e03ad8a13eb50fc37abccd4108249789f45c11183a5fc22af1212fcc0e1' 
  AND token = 'MvxEjaUJ4tIqUK3jSPWY9/C/udGMJzUSdazlDCVpSNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}