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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9144df695331c94e3d5f39b0e7251d7f9868d074c3563c7e10b393d2f07c68f' 
  AND token = 'Uufts4T/4Vb8HUc481TvkvkKDJm+YIpAJNT3P6yhB2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}