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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9819edb6dc658b78cd867f55b6e78ff7ea056787d5b28a27c03a4cd26ad4f7d8' 
  AND token = '4FXNvQMfgyjeDFG/0kAwzmjMzRRWr9Gb6EBWu5kb8B4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}