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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6777f1ca3078310351399c09a8961963f929e412e36b61690a8e38fd819d3abf' 
  AND token = '2yP3spqqRxi2Up+rkjV5PUAhKgxPjlmsiUWY1sDpsbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}