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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd60e172972d696eeeb30d6d844fc369d65f1a873fef1f16cf486384654669f' 
  AND token = 'hapVY5W6ZMTm6ql3onBUTclx7KwOSxcItGqXSdTDMrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}