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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c984e21e0468c0998bb30a8b945c0acb2ea0972075a99a977657491a3ebeeeb4' 
  AND token = 'KZWKHGkm8wSN+nF3wF1G8qlbGpr1Byo6kkb1ODnLkI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}