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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295f5ae3a23637985c05c00c5737d5e2d2d94dfa0d5a9485f3e60a807e6b6c5c' 
  AND token = 'UzA0N/pW77zZjBe5D68kD6kOLR64RITmSUlJNTO9Bnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}