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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e052fae796a6e94e39584ff390888d8a8f009785b04f7427d0a581c37174a08e' 
  AND token = 'CcP45QKs31VgnEaL1taJs059lYvRd/S/m6kyWW4EiqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}