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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '517d7e60eac67cee71009e9a8334de038a1883d59a60f9be443db5c33d0bdf48' 
  AND token = 'EKUIO3u5ru3cPO1KXTy7iO4JE9yQB/dpi7o2EGz+hrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}