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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a903d287a024aeedcc666402d4e3193ec1ae2f555c46b4525b3b16e8eb85176' 
  AND token = '0rN0EkY4h1OWRLdVRfuerk+w863gvZMMWxDyz4AijYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}