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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76d612f3ff824c2eaa8422075b0fc79c22b5f8881c5943e0c0c212da8ccb4624' 
  AND token = 'FQCc/2mhL/a/mDnHzRJ9V5zyiC94yMA/v5fqsIcLGRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}