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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74bbbcc3c45e892b6ef0b514f934fa3eace9ef9ca49aa17561f91feea4e29786' 
  AND token = 'BMySVbBMkS5c53Ikvxh9KKI611JOiC+cm5jhilE71cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}