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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '869d8d7ace5dbcf9b224a70acb70a88bf0d17c502acad4fd23d6f639a77fa3e6' 
  AND token = 'yOfPnzhIpzScXVSfZMqWYBAzSdfu7/6FcfnNAsTqyyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}