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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f735caf8546786e1a4905d633f6dd798ff507475832653b86128345b20d57e9f' 
  AND token = 'd4ShtmiKl4tO1pDB+rFrqMbArgmrNTxMRrkknJ1GYwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}