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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0df2d0b6387cf28d69b4716b420172742edcd1135916c22abaa9caa857a36e95' 
  AND token = 'cmTC4Teu1u3qvRUDRpJ435tBpPFP6KOVxmYkTdXPWdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}