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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f8c2b5e06a8a917066eeeebda829e05857ef368881f1e34146bb70a6826c17' 
  AND token = '9q5w0WArEIISVROV4MOkbicU1of9SPvI+762xnytMTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}