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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b55995eed504fd65978f5b74be7accc73c2a559f1e75d9534c32c9935de6e71' 
  AND token = '8MM3sJ3D5jZx9iremTUTQSau523oGlFMBoNEW1M63ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}