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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82ca0b17796071f8489865fa24ecee506913130870b4520327ae6e6385f5ac35' 
  AND token = 'b0IA3np3LDUXyqdKy7FtZg4nRBxktEd6yixv2o49+L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}