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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e298af94c5a372328b1fc1c50d1f35667293ce2cc994d59834d2ed08b06577' 
  AND token = 'pVrLtmq3LAwlH9F7ZdGpfuK6+DELy/eAFa1fOxf8WYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}