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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '279ee4cd7e61995962476e696f71d1ded370e34334dbcdf5e45a7163fc5e834d' 
  AND token = 'ZmWiGjdUk6MHIk6QJzrL/6TV4RzZDtDO9cuYp9dVOys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}