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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df1ee140da5dc4003db133a3782256fc4093264f9489ef31d5a6f36f278fe21d' 
  AND token = 'SlQ6L8m4USMr0QvO2lu7fBvPKZ5BPt3qEllMKcnfrhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}