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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4e783be7585222c881ab307674bb8a484d5f17f2b274a6a9afe841be18ba10' 
  AND token = 'cfF/P/+JgbXvX6tDT53WNXGkMDgWzbSBgFNfhEBMeCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}