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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '997e888ac20717711aa57b895c8424c21b25a54eeddbc4cd25f12818986ce5a5' 
  AND token = 'uX+ozJihiC3L6JAokS95m2pTzb9halg/yMOeXNdl45s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}