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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721ebc52f6d5b4f9202959e1106dc0a6f3b07f39810bff102d857eb671afbc7e' 
  AND token = 'gLzUjohY1P1Uc0UHsf+o3leO5xOTcwg/zBIlcgW8vXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}