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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5d0ca29aa1d524e3c5c78d143647df26f82fa04d1faae77bdd3ff5f5d035fab' 
  AND token = 'e5Z2ipcTpEz0UVUM++tIeKFRuIMAsdhnpiPstrPceFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}