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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110368b16bedf2491469c3cf2c1232f21feeda33dac1478c975e3cb0678f6b80' 
  AND token = '/rmM8WNSaXecCzehV2NbI7i7pI65JGjjoe6h/0ret0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}