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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3a9ace18965e387c24369ab4a62163a3a70bbc0ef3db5b4275df4409e791249' 
  AND token = 'BpmJV78hOA94RiA+rAAjFSB4WydWpEdJmXYW4xk5bak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}