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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b50d3b5d52bb54a06e329ce32f8cebab865c1226b9dd25106d1f43e26854cd2' 
  AND token = '+QBd7NITTaacYc6eXbJPlcQE1sBDLW1ao597wPr7czc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}