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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df726a72827266ece6ad4d60164730b8d06465a2ff15f045ac8635ac90d25cae' 
  AND token = 'YtubLJdwZ3T9PnRQU0AiYI8/hJXcBRD8q2ID9kvXSYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}