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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4ffc578a2a0b796cf9b903672555001ab81ec4a491874c2a07e14e5495caa1e' 
  AND token = 'hYA0ZSNuuFCq5MH84TS5s9dj72TX1eF9mhBfa4UP4Ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}