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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205cb0df1961d1aa553125ad6d7f6f822d4a124e1d22930a039e741770916e1f' 
  AND token = 'j1D0YZKTIqA5FeGabsyeP8JuXNR+p4sgWMy0hTaVTo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}