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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '552baf6f32a801e98143f468c71531b2d6f20d71d8b0df10b89d690115185d2a' 
  AND token = 'qMRo77T9XkH/zTilUW9n5WYYRX714RFBMDl6Ps7FkW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}