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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0bf85a8c5caf208e5250a8d40d716e5c5235b9f9970420fd7054c41378a43c8' 
  AND token = 'P5ycFpudSsOKpFvDxmyPZH9En+hrEUY6rbxF2/1r/+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}