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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9df7667f9df203287f3e90003fbfef1db67d2f7b5aa6080fa21e890d7365e4e' 
  AND token = 'JKXZ8cXAtmNZAjxA/pn12wo8WTYKBxUr40LfOrkH/ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}