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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c27d0e3d40f6a64181fc67ea6d6a1619570df243acc98343fbbe0590742d22c' 
  AND token = 'Q4yzSrO1zP2ZCj7ntiCFr4C/vF/EvjNSbq9gyKdOHgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}