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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f1c0362e6811bb6d93ca2672fc0def2cdf4b238e8064aaa5b26f4c221501e18' 
  AND token = 'x8bXfarXwwvq6z6hdZa0O3CxdoG7giuHJrP62gkGp2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}