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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e21a06954aac1209caa0df4450f8e1224b7376b2ca3275ea450c3d0181e5a46' 
  AND token = 'BYquPIyEqyomD0sWS9EzQB92aefYHQZcAljAwtYYvcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}