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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e15582c3a98f3dc36c049d31e03f3d37369a46871fcd4e1811840c7ab36ff35' 
  AND token = 'Ds4CjWXcQxjG4Qhl55ju9RubEMmegevO7LpkroaewpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}