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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfa8a726836bdfa0d04a4f9e76b2e28a4fc861a7f1aff9608b4885fd7cc6f074' 
  AND token = '1PNXRsIe6agYONuVFHwNewF4k66hgZBnF8XHQGM/Apw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}