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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc161459390727fed8a51ef7ac6465f3627c07e079db7a6c28faabfac539213' 
  AND token = 'Kmt1+6AJEAoNM5RZbGgcliOyJCES2LVxKqiSwLN9ZVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}