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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e39cfec54059202ff56d6adf80d9970fdc224e830ee670d65dd9949cabd0d0d' 
  AND token = 'TisGrPFgfid8hI5EuwhHZOk/xtiDDL6CPBmfD9KZ/lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}