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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa9323c59fa356c215efcd8d4d35c90fa999e8d34de96262eb17dfe55493ecb8' 
  AND token = 'A8pS3BBrQ1TY0+JLUymT1uTM5p8kW5dsMOX7uUo8XnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}