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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '944c75a0255a107ac1b6d774e75f5d64c7668c5353a75027687cc89d86697456' 
  AND token = 'ORVI/+NzmIrnb/vRiMWL4+xu0iiTv6TXQgfBYx0lZ4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}