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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a39978d521c4e3049bd573c008d59ca4bfdc25832a5bcd1638ca09fbce54e82' 
  AND token = 'Tyx/PSeG0jeW0NgoCitSXsRCuyvn4cVX8dSKfGXV1mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}