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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bc05451e8fdf5b4e040ab58a72aebd9433e71ef6ad690be79635ea7788f3ac' 
  AND token = 'sNBvFvf42GMO4iM+5bIy11/h0yaAsNcLqZAk4xZ+PyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}