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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d43c7c29c232e87deae83914e790cd89bfb840d38564296b8fc4d2f7d1def40' 
  AND token = 'vK0vDVj96W7OKCNXI7jhJ649PaxcrtijkzLtLCklqHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}