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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500561b51ebf204df38f3dd4d0d44ff6100b8e182932e7209a4a212cfc0a9782' 
  AND token = '6XQ3QpS3nbrfrZ8BcWIBBfPKq6yErG0Vfmpswtzo7sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}