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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '409344669cfee56fe39cc6d9d390c5a7055713c6f8bac59cabf8488eef37dedf' 
  AND token = 'NlZD30XaCGp6c/KTQ9TyFvrZ2c7MEadDmw+MONWJhy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}